• Hitaka Y, Isoyama N, Tsuji S (Co-Corresponding), Honda T, Nakayama Y, Yamaguchi M, Nakamura K, Hirata H, Shiraishi K, Asagiri M. Renoprotective effects of laxative linaclotide: Inhibition of acute kidney injury and fibrosis in a rat model of renal ischemia-reperfusion. Biochemical and biophysical research communications. 2024 May;21:709:149709. DOI
   
• Tsuji S, Minami S, Hashimoto R, Konishi Y, Suzuki T, Kondo T, Sasai M, Torii S, Ono C, Shichinohe S, Sato S, Wakita M, Okumura S, Nakano S, Matsudaira T, Matsumoto T, Kawamoto S, Yamamoto M, Watanabe T, Matsuura Y, Takayama K, Kobayashi T, Okamoto T, Hara E. SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response. Nature Aging. 2022 Feb;2(2):115-124. DOI
   
• Kake S, Tsuji S (Co-First), Enjoji S, Hanasaki S, Hayase H, Yabe R, Tanaka Y, Nakagawa T, Liu H.-P., Chang, S.-C., Usui T, Ohama T, Sato K. The role of SET/I2PP2A in canine mammary tumors. Sci Rep. 2017 Jun 27;7(1):4279. DOI

To view a more comprehensive list of publications, please click on the "researchmap" link below.

researchmap

KAKEN

ORCID

Dr. TSUJI Shunya was born in Hyogo Prefecture, Japan, and initially entered the Joint Faculty of Veterinary Medicine at Yamaguchi University (Japan) with the aim of becoming a veterinarian. However, during Dr. TSUJI’s undergraduate studies, his interest shifted toward “exploring the root causes of disease,” which led him to instead pursue basic research, after which he entered the doctoral program at Yamaguchi University in 2016 and obtained his Ph.D. in 2020. After working as a Specially Appointed Researcher and Specially Appointed Assistant Professor at the Research Institute for Microbial Diseases (RIMD) at Osaka University (Japan), Dr. TSUJI was appointed as an Assistant Professor at the Graduate School of Medicine at Yamaguchi University in 2022. Since 2025, Dr. TSUJI has served as an Assistant Professor at the Joint Faculty of Veterinary Medicine at Yamaguchi University.

Aging is defined as the decline of various physical and mental functions over the course of an organism’s, including humankind’s, life cycle. In recent years, research has progressed globally to view aging as a disease, a phenomenon that can be treated and prevented. Dr. TSUJI focuses on “cellular senescence,” which is one of the causes of aging. Dr. TSUJI’s ultimate goal is to increase life expectancy by elucidating the mechanisms that induce “senescent cells” in the body and by 
preventing their generation and accumulation. Dr. TSUJI has also discovered that viral infections, such as COVID-19, are involved in triggering cellular senescence, thus seeks to continue investigation into how senescent cells that emerge from infectious diseases contribute to organismal aging.