Genomic, transcriptomic, proteomic and metabolomics analyses are available as the methodologies for life science research. After working out human genome, detection of rare mutation and expression and structural analysis of proteins as well as exhaustive analyses of genome were also available. Moreover, high resolution of imaging analyses leads to clarify the location of substances and gene expression. Using these methods, you can learn the methodological approach for life sciences
Using mouse that is an important tool of the animal experiment, you can learn about reproductive engineering techniques (such as in vitro fertilization, cryopreservation of fertilized eggs and sperm, embryo transfer and so on) and the protocol of genetically modified animal production. In addition, you can also learn the latest knowledge about studies such as maintenance mechanism of undifferentiated status in ES cells and reproductive technologies of clone animals, and deepen your understanding about mechanism of development and differentiation of the mammalian early stage embryos.
１．Carcinogenesis and progression of pediatric cancers
２．Carcinogenesis and progression of adults cancers
３．Cell immortality and senescence
４．Proliferation and differentiation of mesenchymal stem cells
５．Infection and drug resistance of bacterias
１．Improvement of the reproductive engineering techniques and the protocol of genetically-modified animal production
２．Study on reproductive technologies of clone and monozygotic animals in the mammal
３．Study on undifferentiated status and chimerism of ES cells
【Photo explanation】 Microaspiration of intracellular liquid of target cells using the microtip.
【Photo explanation】 Micromanipulation of fertilized eggs/early stage embryos using the micromanipulator (Generation of chimeric mice by ES cell injection into blastocyst.）