Natural Science Center for Basic Research and Development

Prof. Yusuke Sotomaru

【Research Keyword】
Reproductive engineering technique, experimental animal, genetically-modified animal, clone technology

【Recent highlights】
The common marmosets have been an extremely useful animal model for human diseases research in various fields because they are more closely related than mice or rats to humans. We attempted the technical application of embryonic clone in marmoset and succeeded to produce the first embryonic clone marmoset.

Profiles of Faculty and Research Scholars (Prof. Yusuke Sotomaru)

【Education】
Using mouse that is an important tool of the animal experiment, you can learn about reproductive engineering techniques (such as in vitro fertilization, cryopreservation of fertilized eggs and sperm, embryo transfer and so on) and the protocol of genetically modified animal production. In addition, you can also learn the latest knowledge about studies such as maintenance mechanism of undifferentiated status in ES cells and reproductive technologies of clone animals, and deepen your understanding about mechanism of development and differentiation of the mammalian early stage embryos.

【Research】
１．Improvement of the reproductive engineering techniques and the protocol of genetically-modified animal production
２．Study on reproductive technologies of clone and monozygotic animals in the mammal
３．Study on undifferentiated status and chimerism of ES cells

【Photo explanation】Micromanipulation of fertilized eggs/early stage embryos using the micromanipulator (Generation of chimeric mice by ES cell injection into blastocyst.）


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Graduate School of Biomedical and Health Sciences

1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, Japan 734-8553
TEL: +81-82-257-1705