【Major Papers of the Laboratory】
・Control of parturition timing in pregnant mice by administration of altrenogest via solid feeding, Journal of Experimantal Animal Technology, 57(2), 57-62, 20221230
・miR-582-5p targets Skp1 and regulates NF-Kappa B signaling-mediated inflammation, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 734, 20230115
・GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic nerve crush in mice, NEUROBIOLOGY OF DISEASE, 172, 20221001
【Education】
Using mouse that is an important tool of the animal experiment, you can learn about reproductive engineering techniques (such as in vitro fertilization, cryopreservation of fertilized eggs and sperm, embryo transfer and so on) and the protocol of genetically modified animal production. In addition, you can also learn the latest knowledge about studies such as maintenance mechanism of undifferentiated status in ES cells and reproductive technologies of clone animals, and deepen your understanding about mechanism of development and differentiation of the mammalian early stage embryos.
【Research】
1.Improvement of the reproductive engineering techniques and the protocol of genetically-modified animal production
2.Study on reproductive technologies of clone and monozygotic animals in the mammal
3.Study on undifferentiated status and chimerism of ES cells
【Photo explanation】Micromanipulation of fertilized eggs/early stage embryos using the micromanipulator (Generation of chimeric mice by ES cell injection into blastocyst.)