【Major Papers of the Laboratory】
・J. Arii*, S. Aktar, J. Huang, M. Hirai, Y. Kawamura, H. Miura, B. Wang, S. Nagamata, M. Nishimura, T. Yoshikawa, R. Harris and Y. Mori. A viral APOBEC3 antagonist distinguishes HHV-6A from HHV-6B. Nat. Commun. 17:3566. 2026
・M. Hirai, K. Amaliin, J. Huang, S. Aktar, Y. Mori, J. Arii*. HHV-6B ribonucleotide reductase sequesters NF-κB subunit p65 to inhibit innate immune responses. iScience, 28:111710. 2025
・J. Arii, M. Watanabe, F. Maeda, N. Tokai-Nishizumi, T. Chihara, M. Miura, Y. Maruzuru, N. Koyanagi, A. Kato and Y. Kawaguchi. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat. Commun. 9: 3379. 2018

【Education】
At the undergraduate level, we teach systematic lectures and practical courses in microbiology, including bacteriology and virology, with the aim of helping students acquire fundamental concepts in microbiology and biosafety. At the graduate level, we provide training in virological experimental techniques, as well as molecular biological and biochemical methods, data analysis, and manuscript preparation. Through these educational activities, we aim to foster virology researchers who can contribute internationally.

【Research】
Viruses are small pathogens that enter cells and use cellular systems to replicate, causing a wide range of diseases. Many viral diseases still lack effective treatments or preventive measures. In addition, as exemplified by the emergence of SARS-CoV-2, new pathogenic viruses may continue to emerge in the future. In the Department of Virology, we study how viruses replicate within cells and how they cause disease. Through this research, we aim to contribute to the development of preventive and therapeutic strategies for viral infections.