【Major Papers of the Laboratory】
・Kenichi Nagase*, Hasumi Kuramochi, David W. Grainger, Hironobu Takahashi*, Functional aligned mesenchymal stem cell sheets fabricated using micropatterned thermo-responsive cell culture surfaces, Materials Today Bio, 32, 101657-101456, 20250318
・Azumi Yoshida, Kazuki Baba, Hironobu Takahashi, Kenichi Nagase, Tatsuya Shimizu, One-step fabrication of 3D-aligned human skeletal muscle tissue and measurement of contractile force for preclinical drug testing, Materials Today Bio, 31, 101456-101456, 20250120
・Kenichi Nagase*, Kenji Yamaoka, Ruka Shimane, Naoto Kojima, Norifumi L. Yamada, Hideki Seto, Yoshihisa Fujii, Temperature-dependent behavior of poly(N-isopropylacrylamide) brushes via neutron reflectometry, Surfaces and Interfaces, 54, 105268-105268, 20241019
【Education】
We provide three lectures in basic physical chemistry for undergraduate students.
We are in charge of scientific training for graduate students who are interested in the functional polymers and focused proteomics.
【Research】
We developed innovative purification methods of next generation medicine such as viral vector and exosome using functional polymers. In addition, we developed functional polymers for application to the effective regenerative medicine. Furthermore, we developed an original phosphoproteome technology.
【Figure explanation】Hepatocyte purification using functional polymer
【Figure explanation】Endothelial cell separation using functional polymer and cell affinity peptide
【Figure explanation】Mesenchymal stem cell separation using functional polymer modified silica beads