【Major Papers of the Laboratory】
・Y. Fujikawa, T. Suzuki, H. Kawai, H. Kamiya. NEIL1: the second DNA glycosylase involved in action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine. Free Radic. Biol. Med. 229, 374–383 (March, 2025)
・H. Kawai, K. Sato, T. Kato, H. Kamiya. Correction of substitution, deletion, and insertion mutations by 5'-tailed duplexes.   J. Biosci. Bioengng. 137 (#3), 157–164 (March, 2024)
・Y. Fujikawa, H. Kawai, T. Suzuki, H. Kamiya. Visualization of oxidized guanine nucleotides accumulation in living cells with split MutT. Nucleic Acids Res. 52 (#11), 6532–6542 (June, 2024)
・H. Kawai, R. Iwata, S. Ebi, R. Sugihara, S. Masuda, C. Fujiwara, S. Kimura, H. Kamiya. Development of a versatile high-throughput mutagenesis assay with multiplexed short read NGS using DNA-barcoded supF shuttle vector library amplified in E. coli. eLife 11, e83780 (October, 2022)
・T. Suzuki, Y. Zaima, Y. Fujikawa, R. Fukushima, H. Kamiya. Paradoxical role of the major DNA repair protein, OGG1, in action-at-a-distance mutation induction by 8-oxo-7,8-dihydroguanine. DNA Repair 111, 103276 (March, 2022)

【Education】
(For undergraduates) Quantitative analysis using chemical reactions (volumetric analysis); instrumental analysis; analyses of medicines.
(For graduate students) Overview of nucleic acids; mechanisms of high fidelity DNA replication; nucleic acid medicines.

【Research】
１．Mutagenesis and carcinogenesis induced by DNA damage.
２．Suppression of mutagenesis by DNA repair.
３．Gene therapy by gene correction (genome editing).
４．Mutations and genome stability in iPS cells.
５．Visualization system for damaged nucleotides.