【Major Papers of the Laboratory】
・Jin, Y., Guo, Y., Kawano, Y., Sasatani, M., Ohki, S., Yamane, K., Ota, Y., Tamura, Y., Sotomaru, Y., Baba, Y., and Yasuda, T. T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions. Front. Immunol., 2025. in press
・Guo, Y., Ohki, S., Kawano, Y., Kong, W.S., Ohno, Y., Honda, H., Kanno, M., and Yasuda, T. Eed-dependent histone modification orchestrates the iNKT cell developmental program alleviating liver injury. Front Immunol, 15, 1467774, 2024.
・Shitaoka, K., Higashiura, A., Kawano, Y., Yamamoto, A., Mizoguchi, Y., Hashiguchi, T., Nishimichi, N., Huang, S., Ito, A., Ohki, S., Kanda, M., Taniguchi, T., Yoshizato, R., Azuma, H., Kitajima, Y., Yokosaki, Y., Okada, S., Sakaguchi, T., and Yasuda, T. Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants. Commun Biol, 6, 395, 2023.
・Tamura, Y., Ohki, S., Nagai, H., Yoshizato, R., Nishi, S., Jin, Y., Kitajima, Y., Guo, Y., Ichinohe, T., Okada, S., Kawano, Y., and Yasuda, T. Co-expression of B7-H3 and LAG3 represents cytotoxicity of CD4+ T cells in humans. Front. Immunol., 16, 2025.
・Yoshizato, R., Miura, M., Shitaoka, K., Matsuoka, Y., Higashiura, A., Yamamoto, A., Guo, Y., Azuma, H., Kawano, Y., Ohga, S., and Yasuda, T. Comprehensive method for producing high-affinity mouse monoclonal antibodies of various isotypes against (4-hydroxy-3-nitrophenyl)acetyl (NP) hapten. Heliyon, 10, e40837, 2024.

【Education】
Undergraduate Education (School of Medicine):
Program of Medicine: Lecture and practice of "Immunology" and "Parasitology" (1st and 2nd grade). Practice for Medical Research in Immunology (4th grade).
Program of Health Sciences: Lecture of "Microbiology Immunology" (2nd grade).
Graduate Education:
The Graduate School of Biomedical Sciences offers courses on "Hospital Defense" and "Human Body Functions," and the Graduate School of Integrated Life Sciences offers "Advanced Genome Editing Research B."
In doctoral research guidance, students are given research themes with a view to publishing English research papers, and guidance is given on research and writing papers.

【Reseach】
We study how the immune system is regulated through the antigen receptor, signal transduction, and genetic programs for differentiation and proliferation to overcome infectious diseases, cancer, allergy, autoimmunity, aging, and tissue regeneration.