【Major Papers of the Laboratory】
・Delayed peak antibody titers after the second dose of SARS-CoV-2 vaccine in solid organ transplant recipients: Prospective cohort study, VACCINE, 42(23), 20241003
・Successful outcome achieved with adjuvant chemotherapy with irinotecan plus cisplatin in rectal neuroendocrine carcinoma: a case report, SURGICAL CASE REPORTS, 10(1), 20240919
・Exploratory study on the impact of intraesophageal pressure on quality of life in patients following total gastrectomy: a retrospective cohort study, BMC SURGERY, 24(1), 20240727

【Education】
We are promoting education in the four specialized gastroenterological field, upper gastrointestinal tract, lower gastrointestinal tract, hepatobiliary pancreatic, and transplant fields. We aim to train excellent researchers and transmit their achievements to home and abroad through graduate school studies with high specialty. We also aim to acquire essential surgical skills and practicalize creative problem-solving through participatory clinical training in medical school. We make efforts to train surgeons and surgical scientists who can feel their patient’s pain and suffering and are excellent in researches, skills, scholarship and characters.

【Research】
Aim to provide effective and safe medical treatment closely related to clinical practice, we are working on the following studies.
1．Development of methods for immune-monitoring and induction of immune-tolerance
2．Development of immune-regulatory strategies in xenotransplantation
3．Elucidation of mechanism underlying antibody-mediate rejection
4．Elucidation of characteristics of liver-resident immunocytes
5．Development of approaches for immune-therapy against cancer
6．Elucidation of mechanism underlying liver regeneration
7．Development of measures for patient managements after kidney, pancreas and liver transplantation
8．Development of strategies for ameliorating organ ischemia-reperfusion injury
9．Development of approaches for molecular-targeting therapy against gastroenterological cancer
10．Development of procedures gastroenterological surgeries
11．Development of humanized mouse model for investigating gastroenterological cancer
12．Development of devices for less invasive surgeries
13．Genetic and epigenetic analyses in gastroenterological cancer