【Major Papers of the Laboratory】
・Intestinal overgrowth of Candida albicans exacerbates bleomycin-induced pulmonary fibrosis in mice with dysbiosis, JOURNAL OF PATHOLOGY, 261(2), 227-237, 202310
・Hypoxia-inducible factor 1ﾎｱ modulates interstitial pneumonia-mediated lung cancer progression, JOURNAL OF TRANSLATIONAL MEDICINE, 21(1), 20231127
・Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial-mesenchymal transition in lung endothelial cells, CELL COMMUNICATION AND SIGNALING, 21(1), 20230921

【Education】
Recent progress in medicine and the enhancement of the health care system extended life expectancy, resulting in an unprecedentedly aging society. Along with the aging of the population, there is an increase in the number of patients with internal diseases such as pulmonary and heart diseases; the rehabilitation for these patients has become more important.
In our laboratory, we conduct research and education related to exercise for improving the health status of the elderly, as well as rehabilitation of patients with internal diseases focusing on response of respiration and circulation, immunological function, and oxidative stress during exercise.

【Research】
１．Evaluation of physical function and physical activity of chronic pulmonary disease patients and elderly
２．Evaluation of effect of physical functions and environmental factors on cough peak flow
３．Evaluation of oxidative stress induced by pulmonary rehabilitation
４．Establishment of exercise therapy for chronic pulmonary disease patients focusing on improvement of immunological functions