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【Research Keyword】
microRNA, Telomere, Extracellular Vesicles, Exosome, Nucleic Acid Therapeutics, Aging, Cancer
【Recent highlights】
miR-22 represses cancer progression by inducing cellular senescence, Dan Xu et al. J Cell Biol. 2011 Apr 18; 193(2): 409–424.
http://dx.doi.org/10.1016/j.ebiom.2015.05.025
http://www.sciencedirect.com/science/article/pii/S2352396415300281
【Major Papers of the Laboratory】
・Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas, Nature genetics, 18(1), 65-68, 19980401
・Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas, Cancer Res., 55(13), 2734-2736, 19950401
・Increase in expression level of p21sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts, Oncogene, 10(5), 835-840, 19950401
【Education】
１．Biochemistry V
２．Biochemistry VI
３．Basic Research I
４．Basic Research II
５．Molecular Biology
６．Cell Biology
【Research】
１．MicroRNA in aging and cacner
２．Exosome in aging and cancer
３．Development of annti-cancer drug
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