Bioluminescence Resonance Energy Transfer (BRET), Chemical Biology, Chemical Screening, DNA methylation, DNA recombination, Genome Editing, Genome Engineering, Molecular Evolution, Protein Engineering, Signal Transduction, Transcription Regulation
Nomura laboratory has started as of April 1, 2019. Genome editing is a novel technology with possibility of application in many fields including medicine, drug discovery, and animal/plant breeding. We tackle to develop a novel technology in the field to obtain further knowledge in future. Gene regulation is one of the applicable topics derived from development of genome editing technology. Recently, we have developed a method to regulation orthogonal genes in a single cell (Nomura W, et al. Biochemistry 2019). We also focus on the method to suppress off-target effects for precise genome editing.