【Major Papers of the Laboratory】
・doi: 10.1016/j.jaci.2026.01.020
・doi: 10.1084/jem.20212276
・doi: 10.1016/j.jaci.2021.05.018
・doi: 10.1016/j.jaci.2016.09.035
・doi: 10.1126/science.aaa4282
・doi: 10.1084/jem.20110958

【Education】
The department of Pediatrics provides health care services for physical and mental conditions in children from infancy through adolescence. In our department, 31 pediatricians have each special field, such as hematology, oncology, immunology, neonatology, metabolic disease, neurology, endocrinology, genomics, allergy, rheumatology, cardiology, nephrology, and psychology. We present major point of child health and general pediatric diseases in lecture. Clinical training provide basic attitude for pediatric treatment, interview technique, and physical examination. In graduate course, students can choose several study subjects from the following research contents, and get medical research specialists or advising doctors. In future, we expect our students become leaders of pediatric field.

【Research】

1. Elucidation of the Pathophysiology of Congenital Neutropenia Using iPS Cells and Development of Novel Therapeutic Strategies
2. Elucidation of the Etiology and Pathophysiology of Inborn Errors of Immunity
   Ⅰ) Identification of Causative Genes for Inborn Errors of Immunity Using Multi-Omics Analysis
   Ⅱ) Elucidation of the Pathogenesis of CMC and MSMD
   Ⅲ) Investigation of the Molecular Basis by Which Transcription Factors Cause Inborn Errors of Immunity
   Ⅳ) Establishment of a Genetic Diagnostic System to Improve Diagnostic Yield
3. Development of Highly Sensitive Anti-Neutrophil Antibody Detection Methods
4. Clinical Research on Pediatric Cancers (Hematologic Malignancies and Solid Tumors)
5. Evaluation of Neonatal Immune Function Through Analysis of Regulatory T Cells
6. Pathophysiological Analysis of Patients With Intractable Neurological Diseases Using Neuroimaging and Neurophysiological Examinations
7. Functional Brain Imaging Analysis in Children With Developmental Disorders
8. Elucidation of the Mechanisms Underlying Severe COVID-19
9. Analysis of IL-10 Neutralizing Antibodies in Inflammatory Bowel Disease