HomeHOSTY Association (Graduate School of Advanced Science and Engineering)
Email: bprc*hiroshima-u.ac.jp (Please replace*with @)
Date & Time: May 27,2025
Program
Commentary: Yukihiko MATSUMURA
Professor, Graduate School of Advanced Science and Engineering, Hiroshima University
Lecture: Yusuke HASHIMA
Graduate School of Integrated Sciences for Life, Hiroshima University, M1
“Development of an efficient cell harvesting method utilizing cell aggregation in Aurantiochytrium”
In the fermentative lipid production, the high cost of cell harvesting is a challenge. This study focused on the cell aggregation behavior of mutant strains of Aurantiochytrium sp. to develop an energy-efficient harvesting method. First, we established a novel method for quantifying aggregation activity. Then, we successfully purified the main body of the aggregation-inducing activity. We are currently analyzing its structure-function relationship, and expect that it may be applied not only for cell recovery but also as a novel biomaterial in the future.
Lecture: Kenshi WATANABE
Graduate School of Integrated Sciences for Life, Hiroshima University, Assistant Professor
“Microbial lipid production from non-carbohydrate carbon sources”
Acetic acid, which can be produced at low cost from various biomass, is an ideal carbon source for industrial use of Aurantiochytrium sp., which grow and accumulate useful lipids under heterotrophic conditions. In this study, we searched for breeding targets based on the characteristic gene expression and metabolite profiles of Aurantiochytrium sp. assimilating acetic acid, and established genetically engineered strains with enhanced lipid productivity from acetic acid using our originally developed genome breeding technology.
Lecture: Tsunehiro AKI
Graduate School of Integrated Sciences for Life, Hiroshima University, Professor
“Features and Challenges of the Gas-to-Lipids Bioprocess”
The Gas-to-Lipids bioprocess, which realizes carbon recycling by applying traditional fermentation technology, is a promising biotechnology with extremely high carbon conversion efficiency and as a result, is expected to output a wide variety of lipid products. In this presentation, I will discuss its technical features, challenges to be overcome, and solutions.
Chair: Yukihiko MATSUMURA
Professor, Graduate School of Advanced Science and Engineering, Hiroshima University
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