Oral cancer, molecular pathology, periodontal disease, tissue regeneration, salivary gland tumor, odontogenic tumor and histopathological diagnosis
・We determined ameloblastin, an enamel matrix protein, is related to bone formation and inhibition of proliferation and differentiation of osteosarcoma.
・We found the role of lactoferrin in periodontitis and rheumatoid arthritis as an agent for prevention and therapy.
・We determined the role of VEGF-Flt-1 signaling in bone invasion in oral cancer.
・We determined periodontal pathogens could reach liver via blood circulation and cause progression of liver fibrosis through TGF-beta and Galectin-3 production. Elimination of periodontal pathogen by antibiotic reduced liver inflammation and fibrosis.
・We determined dental infection with periodontal pathogens induced preterm birth through Galectin-3.
・We have won various prizes during the past 5 years including five by staff members, 9 by graduate students and 15 by undergraduate students who are members of our laboratory.