Orthodontics and Craniofacial Developmental Biology

Prof. Kotaro Tanimoto

【Research Keyword】
Orthodontic force, craniofacial growth, temporomandibular disorders (TMD), amelogenesis imperfecta, genetic diagnosis, regeneration medicine

【Recent highlights】
Many postgraduate students have been sent to overseas research institutions to experience advanced research. Concurrently, we accept
foreign students from various countries to accomplish active international exchange. Recently in our research, we developed a new modality optimized for bone regeneration of the jaw cleft using bone marrow-derived mesenchymal stem cells and a novel scaffold, unsintered carbonated-hydroxyapatite granules. We are applying this method in clinical practice.

Profiles of Faculty and Research Scholars

Orthodontics, an area of dentistry that treats teeth alignment and bite malocclusions, contributes to the general well-being of people through good mouth health.
We lecture on the basic dental sciences regarding orthodontics, clinical orthodontics including orthodontic treatment, dentofacial orthopedics, and surgical orthodontics; this allows precise orthodontic diagnosis and treatment. In addition, the Course for Clinical Dental Science provides a practical training in orthodontic tooth movement using multi-bracket appliances to show orthodontic treatment. The Postgraduate Course in Orthodontics has classes to acquire certification as an orthodontic specialist for an advanced professional specialty.

Contents of research

  1. Elucidation of pathogenic mechanism in malocclusion and management of oral maxillofacial skeletal growth.
  2. Optimization of tooth movement by orthodontic force.
  3. Establishment of a new orthodontic treatment based on the image and biochemical diagnosis of temporomandibular disorders (TMD).
  4. Bone regeneration using mesenchymal stem cells and the development of regeneration medicine for closure of the jaw cleft.
  5. Elucidation of pathogenesis of amelogenesis imperfecta and the restoration of tooth enamel by application of a bio-mineralization process.
  6. Evaluation of the contribution of various oral functions to general fitness.
  7. Development of new instruments and materials for orthodontic treatment.