上野 聡 教授 / UENO Satoru Professor


Clarification of crystallization and crystal structure for edible solid fats such as chocolate and margarine, and emulsion system such as mayonnaise. We are also studying the relationship between crystallization and/or crystal structure and deliciousness of edible solid fats.

keywords:crystallization, triacylglycerol, ultrasound stimulation, fats, polymorphic crystallization, W/O)", winter adaptation, triacylglycero

  1. Synchrotron radiation microbeam X-ray analysis of microstructures and the polymorphic transformation of spherulite crystals of trilaurin/Cryst. Growth Design/2008
  2. In-situ studies of ultrasound-stimulated fat crystallisation using synchrotron radiation/J. Phys. Chem. B/2003
  3. Fat Bloom Caused by Partial De-Oiling on Chocolate Surfaces after High-Temperature Exposure/J. Am. Oil Chem. Soc./2021
川井 清司 教授 / KAWAI Kiyoshi Professor


To improve and control food processing, preservation, and texture, thermal and rheological property changes (crystallization, melting, glass to rubber transition, and complex formation) of foods and biomaterials are investigated. For example, frozen foods, freeze-dried foods, starch and starchy foods, powders, and lactic acid bacteria are employed as  samples.

keywords:food processing, preservation, texture, thermal property, rheological property

  1. Effect of sugar composition on the water sorption and softening properties of cookie. Food Chem, 145, 772-776: 2014. 
  2. Effect of stepwise baking without starch melting on the macroscopic structure, browning, texture, and in vitro starch digestibility of cookie. Food Sci Technol, 66: 384-389, 2016.
  3. Effect of glass transition on the hardness of a thermally compressed soup solid. J Food Eng, 247: 38-44, 2019.
三本木 至宏 教授 / SAMBONGI Yoshihiro Professor


Clarifying the structure and function of proteins required for microbial energy metabolism, thereby learning the mechanism for organisms to live. Also focusing on the fermentation process as a form of energy metabolism, hoping to leverage basic findings in the food industry.

keywords:energy metabolism protein, fermentation

  1. Expression of two glutamate decarboxylase genes in Lactobacillus brevis. Biosci Biotech Biochem 84:1069-1072.(2020)
  2. Response of neutrophilic Shewanella violacea to acid stress: Growth rate, organic acid roduction, and gene expression. Extremophiles 23:319-326.(2019)
  3. Stability of cytochromes c' from psychrophilic and piezophilic Shewanella species: Implications for complex multiple adaptation to low temperature and high hydrostatic pressure. Extremophiles 23:239-248.(2019)
島田 昌之 教授 / SHIMADA Masayuki Professor


My special field is the reproductive biology to clarify the testis and ovarian function from the viewpoints of molecular biology and molecular endocrinology. I’m doing the translational study from the basic research to contribute to infertility care and animal reproductive technology.

keywords:reproductive aging, senescent cell, epigenetic regulation, fibrosis, metabolomic activity

  1. ERK1/2 in ovarian granulosa cells are critical for female fertility. Science, 324; 938-941.(2009)
  2. Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm. PLoS Biol 17:e3000398.(2019)
  3. A simple sperm-sexing method that activates TLR7/8 on X sperm for the efficient production of sexed mouse or cattle embryos. Nat Protoc15:2645-2667.(2020)
島本 整 教授 / SHIMAMOTO Tadashi Professor


From the viewpoint of food safety, we are conducting research on the analysis of virulence-related genes of foodborne pathogenic bacteria such as Vibrio spp. and the mechanism of inter-bacterial transmission of antimicrobial resistance genes via mobile genetic elements, as well as the development of norovirus inactivation methods and anti-noroviral disinfectants.

keywords:foodborne pathogenic bacteria, virulence-related genes, antimicrobial resistance genes, mobile genetic elements, norovirus

  1. Comparative molecular profiling of antimicrobial resistance and phylogenetic characterization of multidrug-resistant Escherichia coli isolated from meat sources in 2009 and 2021 in Japan. Int J Food Microbiol 391-393: 110146(2023)
  2. Sequence polymorphisms in Vibrio cholerae HapR affect biofilm formation under aerobic and anaerobic conditions. Appl Environ Microbiol 88: e01044-22(2022)
  3. Antiviral effects of persimmon extract on human norovirus and its surrogate, bacteriophage MS2. J Food Sci 79: M941-M946(2014)
鈴木 卓弥 教授 / SUZUKI Takuya Professor


Defects in the intestinal barrier increase the penetration of luminal inflammatory molecules into the intestinal mucosa and are closely associated with both intestinal and extra-intestinal diseases. Our research group investigates the roles of food factors and nutrients in regulation of intestinal barrier and inflammation and explores their therapeutic potentials.

keywords:dietary fibers, polyphenols, intestinal barrier, microbiota, tight junction

  1. Bioactive factors secreted by Bifidobacterium breve B-3 enhance barrier function in human intestinal Caco-2 cells. Benef Microbes 10: 89 (2019)
  2. Exopolysaccharides from Leuconostoc mesenteroides attenuate chronic kidney disease in mice by protecting the intestinal barrier. J Functional Foods 52: 276(2019)
  3. Dietary Fermentable Fibers Attenuate Chronic Kidney Disease in Mice by Protecting the Intestinal Barrier. J Nutr 148: 552(2018)
中江 進 教授 / NAKAE Susumu Professor


Based on the search results for genes involved in acute and chronic inflammatory diseases such as allergy and autoimmunity, our purpose is to elucidate how those genes are involved in the development of such diseases using the mouse models.

keywords:immunology, allergy, autoimmunity, mouse disease model, cytokine

  1. IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice. Sci Rep. 9:17067(2019)
  2. IL-25 enhances TH17 cell-mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells. J Allergy Clin Immunol. 142:1500-1509(2018)
  3. An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers. Immunity. 43:175-186(2015)
長沼 毅 教授 / NAGANUMA Takeshi Professor


The Applied Environmental Life Science Lab investigates characteristics of lives in extreme environments such as deep sea, deep subsurface, volcanoes and Antarctica as well as in non-extreme environments, and seeks their applicability directions. Possibilities of extraterrestrial lives and human habitations in outer space are also studied.

keywords:extreme environment, extraterrestrial life

  1. Enhanced bacterial growth and gene expression of D-amino acid dehydrogenase with D-glutamate as the sole carbon source. Front. Microbiol. 9, 2097(2018)
  2. Oligoflexus tunisiensis gen. nov., sp. nov., a Gram-negative, aerobic, filamentous bacterium of a novel proteobacterial lineage, and description of Oligoflexaceae fam. nov., Oligoflexales ord. nov. and Oligoflexia classis nov. Intl. J. Syst. Evol. Microbiol. 64, 3353-3359(2015)
  3. Phylotype diversity of deep-sea hydrothermal vent prokaryotes trapped by 0.2- and 0.1-μm-pore-size filters. Extremophiles 11, 637-646(2007)
西堀 正英 教授 / NISHIBORI Masahide Professor


Our goals are to clarify the history of origin and transmission of livestock(camels, pigs, chickens, etc.)in the world based on genomic DNA information, to clarify genetic diversity of those animals, and genetically elucidate animal ecology through metagenomics and environmental DNA analysis.

keywords:genomic DNA, genetic diversity, metagenomics, environmental DNA

  1. Unveiling new perspective of phylogeography, genetic diversity, and population dynamics of Southeast Asian and Pacific chickens. Scientific Reports, 12:14609.(2022)
  2. Origin and demographic history of Philippine pigs inferred from mitochondrial DNA. Frontiers in Genetics,12:823364.(2022)
  3. Unraveling the history of the genus Gallus through whole genome sequencing. Mol Phylogenet Evol, 158:107044(2021)
西村 慎一 教授 / NISHIMURA Shinichi Professor


Which, how, and why metabolites control organisms? We focus on microbial metabolites with antibiotic and symbiotic activities. By unveiling molecular mechanisms underlying such activities, we would like to understand the life and contribute to a better life of humanity.

keywords:natural product, chemical biology, antibiotics, symbiotics

  1. FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast. iScience, 25:105659(2022)
  2. Ferrichrome, a fungal-type siderophore, confers high ammonium tolerance to fission yeast. Sci. Rep. 12:17411(2022)
  3. Differential biosynthesis and roles of two ferrichrome-type siderophores, ASP2397/AS2488053 and ferricrocin, in Acremonium persicinum. ACS Chem. Biol. 17:207-216(2022)
羽倉 義雄 教授 / HAGURA Yoshio Professor


Both basic and applied research in Food Engineering is conducted. Particularly, we focus on the following main topics: Measurement of the food manufacturing process using electrical properties, Measurement and evaluation of mechanical properties of foods, including texture, and Mechanical processing of food using low-temperature mechanical properties(e.g., cryo-cutting, cryo-shattering).

keywords:food manufacturing process, electrical properties, mechanical properties, texture, mechanical processing of food, low-temperature

  1. Nondestructive determination of the rheological properties of liquid food in sealed retort pouches. J. Food Process Preserv, 42: e13651.(2018)
  2. Estimation of Hardness of Cooked Rice during Retort Sterilization by Electric Impedance Measurement. Journal of The Japanese Society for Food Science and Technology, 66:469(2019)
  3. Influence of physical properties on the taste and flavor of strawberry jam. J Texture Stud, e12582.(2021)
細野 賢治 教授 / HOSONO Kenji Professor


I study food value chain and develop methods of securing sustainable food and resource, from the viewpoint of Socio-Economic Agricultural Science. I have studied the structure and mechanism of food value chain, and developed strategies of food marketing and rural promotion.

keywords:food value chain, food marketing, agricultural structure and mechanism, rural promotion

  1. Competitive Advantage Factors in Vertically Diversified Brand Chicken Business: A Partial Value Chain Analysis of a Japanese Poultry Wholesaler, Japan Agricultural Research Quarterly, 54: 327-333.(2020)
  2. Constructing the Value Chain for Promotion of Lemon Production in Hiroshima Prefecture, Japan, Agricultural Marketing Journal of Japan, 27: 46-53.(2018)
  3. Existence Conditions of Rural Community Business, Journal of Rural Economics, 91: 23-28.(2019)
堀内 浩幸 教授 / HORIUCHI Hiroyuki Professor


Basic research area: Avian stem cell biology, Avian immunobiology, Avian embryogenesis. Applied research area: Production of genetic-modified and genome editing domestic poultry. Study on elucidation of sex determination in chickens, highly pathogenic avian influenza(HPAIV), and development of useful chicken and/or mouse monoclonal antibodies(mAbs).

keywords:genome editing, sex determination, HPAIV, mAbs

  1. Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice. PLOS Pathog. 1008823(2020)
  2. An improved protocol for stable and efficient culturing of chicken primordial germ cells using small-molecule inhibitors. Cytotechnology 72:397-405(2020)
  3. Comparison of sex determination mechanism of germ cells between birds and fish: Cloning and expression analyses of chicken forkhead box L3-like gene. Dev. Dyn. 248:826-836(2019)
矢中 規之 教授 / YANAKA Noriyuki Professor


The number of people who have obesity, diabetes, and cancers has been increasing with the westernization of diets, and it has become a big social problem. We are trying to elucidate nutrients and food factors preventing these illnesses at the molecular and genetic levels by using new gene knockout mice.

keywords:food, nutrients, obesity, diabetes

  1. The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin treatment. Sci. Rep. 9:14101.(2019)
  2. Serum amyloid A3 gene expression in adipocytes is an indicator of the interaction with macrophages. Sci. Rep. 6:38697.(2016)
  3. New members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activity. J. Biol. Chem. 290:4260-4271.(2015)
大村 尚 准教授 / OOMURA Hisashi Associate Professor


Chemical ecology is the interdisciplinary research field to understand the origin, function, and significance of natural products that mediate biological interactions in the ecosystem. Using butterflies, I aim to discover bioactive compounds involved in their mating, oviposition, and defense against predation, and to apply these chemicals to crop protection.

keywords:semiochemical, pheromone, allelochemical, butterfly, plant, bioassay, organic chemistry, behavior, chemical sense, evolution, speciation, chemotaxonomy

  1. Role of trisaccharides in larval secretion of Lycaeides argyrognomon butterfly on ant attendance. J. Insect Physiol. 150: 104558. (2023)
  2. Polyhydroxy acids as fabaceous plant components induce oviposition of the common grass yellow butterfly, Eurema mandarina. J. Chem. Ecol. 49: 67-76. (2023)
  3. Sex pheromones from male forewings of the common grass yellow Eurema mandarina. J. Chem. Ecol. 48: 518-530. (2022)
冲中 泰 准教授 / OKINAKA Yasushi Associate Professor


Fish diseases have caused significant economic losses to the global aquaculture industry. In order to develop a method to control fish diseases drastically, we are investigating host-pathogen interactions in molecular biological aspects.

keywords:fish diseases, host-pathogen interactions

  1. Identification of RNA regions that determine temperature sensitivity in betanodaviruses. Arch. Virol. 155: 1597-1606.(2010)
  2. Comparisons among the complete genomes of four betanodavirus genotypes. Dis. Aquat. Org. 80: 113-121.(2008)
  3. Betanodavirus infection in the freshwater model fish medaka(Oryzias latipes). J. Gen. Virol. 87: 2333-2339.(2006)
国吉 久人 准教授 / KUNIYOSHI Hisato Associate Professor


I am interested in the metamorphosis from asexual stage(polyps)to sexual stage(jellyfish)in the life cycle of jellyfish, and I am studying the molecular mechanisms of metamorphosis in the moon jellyfish using techniques from organic chemistry and molecular biology.

keywords:jellyfish, metamorphosis, bioactive substances

  1. Role of cell proliferation in strobilation of moon jellyfish Aurelia coerulea. Fish. sci. 90: 179–190 (2024)
  2. Molecular characterization of aspartylglucosaminidase, a lysosomal hydrolase upregulated during strobilation in the moon jellyfish, Aurelia aurita. Biosci. Biotech. Biochem. 81: 938–950 (2017)
  3. Indomethacin induction of metamorphosis from the asexual stage to sexual stage in the moon jellyfish, Aurelia aurita. Biosci. Biotech. Biochem. 76: 1397-1400 (2012)
小泉 晴比古 准教授 / KOIZUMI Haruhiko Associate Professor


Research on the improvement in the quality of protein crystals, which is important for elucidating biological functions and drug discovery, has been performed by applying an electric field and controlling the hydration structure. In the future, this technique will also be applied to materials related to food, including pharmaceuticals.

keywords:electric field, hydration structure, crystal growth, crystal quality

  1. Effect of Accumulated Strain on Fat Bloom in CBS-Based Compound Chocolates. CrystEngComm 25: 4562-4567(2023)
  2. Control of Phase Separation for CBS-Based Compound Chocolates Focusing on Growth Kinetics. Cryst Growth Des 22: 6879–6885(2022)
  3. Theoretical and Practical Studies on Effects of External Electrostatic Electric Field on Nucleation and Growth Kinetics of Protein Crystals. Prog Cryst Growth Charact Mater 68: 100568(2022)
田中 若奈 准教授 / TANAKA Wakana Associate Professor


I am interested in how plants elaborate their structures such as flowers and branches. My research objective is to elucidate the molecular and genetic mechanisms underlying the control of plant development.

keywords:branch formation, flower development, meristem, plant stem cells, rice

  1. Flower meristem maintenance by TILLERS ABSENT 1 is essential for ovule development in rice. Development 148: dev199932 (2021)
  2. Antagonistic action of TILLERS ABSENT1 and FLORAL ORGAN NUMBER2 regulates stem cell maintenance during axillary meristem development in rice. New Phytol. 225: 974-984 (2020)
  3. Axillary meristem formation in rice requires the WUSCHEL ortholog TILLERS ABSENT1. Plant Cell 27: 1173-1184 (2015)
長命 洋佑 准教授 / CHOMEI Yosuke Associate Professor


My research theme is about problems and issues emanating from agricultural production to food consumption in agricultural and rural communities, mainly through fieldwork in Japan and overseas(China, Europe…etc.). My major specialty are agricultural management and agricultural economics. The main subjects of the survey are dairy farming and beef cattle farming.

keywords:dairy management, beef cattle management, innovation, fieldwork, questionnaire survey

  1. 酪農経営の変化と食料・環境政策―中国内モンゴル自治区を対象として/養賢堂/2017
  2. 稲作法人経営における多角化戦略と経営革新/農林業問題研究/2018
  3. 牛肉の購買行動における消費者意識構造の把握―共分散構造分析を用いた解析―/農林業問題研究/2016
中山 達哉 准教授 / NAKAYAMA Tatsuya Associate Professor


Our aim is to contribute to food safety by acquiring scientific knowledge on bacteria. Research is promoted through an extensive network of national and international universities and research institutions in three research topics: foodborne pathogens, bacterial resistance and microbiota.

keywords:food microbiology, food hygiene, food poisoning bacteria, antibiotic resistant bacteria, microbiota

  1. Abundance of colistin-resistant Escherichia coli harbouring mcr-1 and extended-spectrum beta-lactamase-producing E. coli co-harbouring blaCTX-M-55 or -65 with blaTEM isolates from chicken meat in Vietnam, Arch Microbiol, 204, pp. 137(2022)
  2. Isolation of carbapenem-resistant Enterobacteriaceae harbouring NDM-1, 4, 5, OXA48 and KPC from river fish in Vietnam, Food Control, pp.108594(2022)
  3. Long-term grow-out affects Campylobacter jejuni colonization fitness in coincidence with altered microbiota and lipid composition in the cecum of laying hens, Front Vet Sci, pp.675570(2021)
船戸 耕一 准教授 / FUNATO Kouichi Associate Professor


We are investigating the transport mechanisms that determine the subcellular localization of lipids and lipid-modified proteins, and their roles in cellular functions at the molecular-genetic level. We are also developing applied researches for mass production of lipids using yeast as a host.

keywords:lipid, lipid-modified protein, transport, cellular function, genetics, yeast, metabolic engineering

  1. Membrane contact sites regulate vacuolar fission via sphingolipid metabolism. Elife, 12:RP89938 (2024)
  2. Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites. Cell Rep., 39:110768(2022)
  3. Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast. J. Cell Biol., 155:949(2001)
カムランシー タナッチャポーン 准教授 / KUMRUNGSEE Thanutchaporn Associate Professor

My research interests are in elucidation of food factors with potent preventive effects on lifestyle-related diseases and their mechanisms. Currently, I am interested in exploring roles of imidazole dipeptides in muscle regeneration and brain functions as well as focusing on regulation of GABA metabolism to prevent obesity.

keywords:skeletal muscle, muscle stem cells(satellite cells), muscle regeneration, functional foods, bioactive compounds, carnosine/homocarnosine, obesity, GABA, vitamin B6

  1. Dietary GABA and its combination with vigabatrin mimic calorie restriction and induce antiobesity-like effects in lean mice. Journal of Functional Foods 78:104367.(2021)
  2. Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles. Amino Acids 52:743–753.(2020)
  3. Novel metabolic disturbances in marginal vitamin B 6 -deficient rat heart. Journal of Nutritional Biochemistry 65:26–34.(2019)
平山 真 講師 / HIRAYAMA Makoto Associate Professor or Lecturer


Research to elucidate the molecular basis of the unique glycan recognition of sugar-binding proteins "lectins" from algae and to develop them as pharmaceuticals(anticancer, antiviral, etc.), biochemical reagents (glycan/cell identification, tumor marker detection), and health food materials.

keywords:lectin, alga, glycan, anticancer, antiviral, tumor marker, health food

  1. A novel high-mannose specific lectin from the green alga Halimeda renschii exhibits a potent anti-influenza virus activity through high-affinity binding to the viral hemagglutinin. Mar Drugs 15: 255.(2017)
  2. High-mannose specific lectin and its recombinants from a carrageenophyta Kappaphycus alvarezii represent a potent anti-HIV activity through high-affinity binding to the viral envelope glycoprotein gp120. Mar Biotechnol 18: 144-160.(2016)
  3. High mannose-binding lectin with preference for the cluster of α1–2-mannose from the green alga Boodlea coacta Is a potent entry inhibitor of HIV-1 and Influenza viruses. J Biol Chem 286: 19446-19458.(2011)
藤川 愉吉 講師 / FUJIKAWA Yukichi Associate Professor or Lecturer


Plants have to compromise their yield potential for their tolerance towards environmental stress. To develop stress-tolerant/resistant plants with the level of their yield potential maintained or improved, we are conducting biochemical research on the expression and function of enzymes and proteins involved in plant stress.

keywords:biochemical research, environmental stress, enzymes, plant

  1. Split luciferase complementation assay to detect regulated protein-protein interactions in rice protoplasts in a large-scale format./Rice/2014
  2. Luminescence dvetection of SNARE–SNARE interaction in Arabidopsis protoplasts/Plant Mol. Biol./2010
  3. Split luciferase complementation assay to study protein-protein interactions in Arabidopsis protoplasts/Plant J./2007
生谷 尚士 助教 / IKUTANI Masashi Assistant Professor


Our research team conducts research on immune cells, which are involved in allergic diseases including asthma and atopic dermatitis. To explore the causes of these immune-related diseases, we study the dynamics of particular immune cells, such as ILC2 and eosinophil, as well as cytokines that regulate these cells.

keywords:allergy, ILC2, eosinophil, cytokine

  1. Elimination of eosinophils using anti-IL-5 receptor alpha antibodies effectively suppresses IL-33-mediated pulmonary arterial hypertrophy, Immunobiology, 223, 486-492(2018)
  2. Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy, JCI Insight, 2, e90721(2017)
  3. Identification of Innate IL-5-Producing Cells and Their Role in Lung Eosinophil Regulation and Antitumor Immunity, J Immunol, 188, 703-713 (2012)
池田 敦子 助教 / IKEDA Atsuko Assistant Professor


Ceramide is the essential lipid that controls cellular functions. My research interests are the molecular mechanisms of ceramide homeostasis(synthesis, transport, and metabolism)via the various intracellular organelles.

keywords:ceramide, lipid transport, membrane contact site, yeast

  1. Tricalbins Are Required for Non-vesicular Ceramide Transport at ER-Golgi Contacts and Modulate Lipid Droplet Biogenesis. iScience, 23:101603(2020)
  2. Membrane Contact Sites in Yeast: Control Hubs of Sphingolipid Homeostasis. Membranes, 11:971(2021)
  3. Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast. J Cell Sci., 127:376-87(2014)
冨永 淳 助教 / TOMINAGA Jun Assistant Professor


If you are interested in smart crop production, this is the right place! My lab focuses on photosynthesis for improved crop management and productivity, though I am very interested in the biology of photosynthesis. I also try to address questions involving climate change, stress physiology, and sustainable agriculture.

keywords:photosynthesis, gas exchange, phenomics, physiological ecology of land plants/crops

  1. Overexpression of BUNDLE SHEATH DEFECTIVE 2 improves the efficiency of photosynthesis and growth in Arabidopsis. Plant J 102: 129-137.(2020)
  2. Direct measurement of intercellular CO2 concentration in a gas-exchange system resolves overestimation using the standard method. J Exp Bot 69: 1981-1991.(2018)
  3. Cuticle affects calculations of internal CO2 in leaves closing their stomata. Plant Cell Physiol 56: 1900-1908.(2015)
藤井 創太郎 助教 / FUJII Sotaro Assistant Professor

Nitric oxide(NO)has a positive side that functions as a signaling molecule in vivo, but it also has a negative side that is cytotoxic. In our laboratory, we are studying how microorganisms cope with and handle NO.

keywords:microorganism, nitrigen cycle, heme protein

  1. Structural and functional insights into thermally stable cytochrome c' from a thermophile. Protein Sci 26:737-748.(2017)
松崎 芽衣 助教 / MATSUZAKI Mei Assistant Professor


Our goal is to develop genetic modification technology using genome editing in birds, and to apply it to the pharmaceutical and food industries. In addition, we focus on the molecular mechanisms of avian reproductive systems and the development of reproductive technologies based on these mechanisms in poultry.

keywords:genome-editing, avian reproduction

  1. Lactic acid is a sperm motility inactivation factor in the sperm storage tubules/Sci. Rep.(2015)
  2. Longer and faster sperm exhibit better fertilization success in Japanese quail/Poult. Sci.(2021)
  3. Effect of sperm surface oligosaccharides in sperm passage into sperm storage tubules in Japanese quail(Coturnix japonica), Anim. Rep. Sci.(2021)
山本 祥也 助教 / YAMAMOTO Yoshinari Assistant Professor


The purpose of our research is to explore the immunomodulatory effects of foods and microorganisms, and then to utilize their function to develp functional foods that prevent and reduce some diseases such as infectious, inflammatory and allergic diseases.

keywords:food immunology, microorganism, functional food, mice, cell culture, oral administration

  1. Class A CpG Oligonucleotide Priming Rescues Mice from Septic Sock via Activation of Platelet-Activating Factor Acetylhydrolase. Front Immunol.(2017)
  2. Oral Administration o Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice. Front Immunol.(2020)
  3. Inhibitory/Suppressive Oligodeoxynucleotide Nanocapsules as Simple Oral Delivery Devices for Preventing Atopic Dermatitis in Mice. Mol Ther.(2015)
カイゴイ ジャン クレス カイングレット 助教 / CAIGOY JANT CRES CAINGLET Assistant Professor

I study on understanding the phosphorelay regulation of virulence and biofilm formation of bacterial foodborne pathogens. Currently, I am interested in elucidating the function of the ArcAB system, a two-component system activated under low oxygen conditions, in cholera pathogenesis. 

keywords:foodborne bacteria, virulence, phosphorelay system, quorum-sensing, ArcAB system, HapR, Vibrio cholerae, biofilm formation

  1. Antibacterial, antibiofilm, and antimotility signatures of some natural antimicrobials against Vibrio cholerae. FEMS Microbiol. Lett., 369:fnac076 (2022)
  2. Sequence polymorphisms in Vibrio cholerae HapR affect biofilm formation under aerobic and anaerobic conditions. Appl. Environ. Microbiol., 88:e0104422 (2022)
  3. Isolation and identification of photosynthetic bacteria (PSB) from processing wastewater and its biomass production using supplemental nutrient sources. Phil. J. Nat. Sci., 1:37-47 (2016)
ゼジロ クリスチアン 特任助教 / XEDZRO CHRISTIAN Assistant Professor (Special Appointment)

My research focuses on the molecular analysis/epidemiology of antimicrobial resistance (AMR) and virulence-associated factors of foodborne bacteria using One Health surveillance systems. My aim is to reveal detailed map of AMR pathogens and the mechanisms of transmission of AMR genes through mobile elements, such as plasmids.

keywords:one health, foodborne bacteria, antimicrobial resistance, virulence-associated factors, plant antimicrobials

  1. Predominance of multidrug-resistant Gram-negative bacteria isolated from supermarket retail seafood in Japan. Microorganisms 11: 2935 (2023)
  2. Comparative molecular profiling of antimicrobial resistance and phylogenetic characterization of multidrug-resistant Escherichia coli isolated from meat sources in 2009 and 2021 in Japan. Int J Food Microbiol 391-393: 110146 (2023)
  3. Antibacterial efficacies and time-kill kinetics of indigenous Ghanaian spice extracts against Listeria monocytogenes and some other foodborne pathogenic bacteria. Microbiol Res 258 126980 (2022)
奥田 将生 客員教授 / OKUDA Masaki Visiting Professor


Our research focus is the understanding of the properties of the ingredient rice grains and water for sake making to make high quality of sake and shochu. We are investigating the influences of meteorological conditions during rice growing on sake making process, and the compounds affecting sake quality.

keywords:sake, shochu, rice, water, meteorological condition

  1. Rice used for Japanese sake making, Biosci. Biotechnol. Biochem., 83,1428-1441(2019)
  2. Relationship between sake making properties of rice grains and meteorological data. J.Brew.Soc., 104:699-711(2009)in Japanese
  3. Structural and retrogradation properties of rice endosperm starch affect enzyme digestibility of steamed milled-rice grains used in sake production. Cereal Chemistry, 83: 143-151(2006)
正木 和夫 客員教授 / MASAKI Kazuo Visiting Professor


I am studying microbiology(yeast and koji-mold)for brewing. In particular, the main targets are elucidation of functions, breeding, and enzymatic research. I am also interested in exploring new enzymes, developing new uses, and mass-producing enzymes. 

keywords:enzyme, yeast, koji-mold, brewing microbiology

  1.  Aspergillus oryzae acetamidase catalyzes degradation of ethyl carbamate, J Biosci Bioeng,130, 577(2020)
  2. Construction of a new recombinant protein expression system in the basidiomycetous yeast Cryptococcus sp strain S-2 and enhancement of the production of a cutinase-like enzyme, Appl Microbiol Biotechnol, 93, 1627(2012)
  3. Cutinase-like enzyme from the yeast Cryptococcus sp strain S-2 hydrolyzes polylactic acid and other biodegradable plastics, Appl Environ Microbiol, 71, 7548(2005)