石田 敦彦 教授 / ISHIDA Atsuhiko Professor


I am interested in intracellular signal transduction, especially protein phosphorylation and dephosphorylation. I am studying multifunctional CaM kinases, which play important roles in Ca2+ signaling, and CaM kinase phosphatase (PPM1F) involved in their regulation. The latter has been found to be involved in various diseases such as cancer and depression.

keywords:phosphorylation, dephosphorylation, biochemistry, molecular biology, chemical biology, enzyme inhibitor

  1. Autoactivation of C-terminally truncated Ca 2+ /calmodulin-dependent protein kinase(CaMK)Iδ via CaMK kinase-independent autophosphorylation Arch. Biochem. Biophys. 668 29 - 38(2019)
  2. Functions and dysfunctions of Ca2+ /calmodulin-dependent protein kinase phosphatase(CaMKP/PPM1F)and CaMKP-N/PPM1E Arch.Biochem. Biophys. 640 83 - 92(2018)
  3. The phosphatase-resistant isoform of CaMKI, Ca2+ /calmodulin-dependent protein kinase Iδ(CaMKIδ), remains in its 'Primed' form without Ca2+ stimulation. Biochemistry 54 3617 - 3630(2015)
浮穴 和義 教授 / UKENA Kazuyoshi Professor


I have identified novel neuropeptides in the avian and rodent brain and elucidated their molecular mechanisms, especially instinctive behavior such as appetite and regulation of energy metabolism. I am aiming for discoveries in the field of neurometabolic and neuroendocrine regulations. 

keywords:neuropeptide, energy metabolism, neurometabolism, neuroendocrinology

  1. Avian and murine neurosecretory protein GL participates in the regulation of feeding and energy metabolism. Gen. Comp. Endocrinol. 260:164-170 (2018) 
  2. Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity. eLife 6:e28527 (2017) 
  3. Neurosecretory protein GL, a hypothalamic small secretory protein, participates in energy homeostasis in male mice. Endocrinology 158:1120-1129 (2017)
久我 ゆかり 教授 / KUGA Yukari Professor


My research themes are the symbioses between plants and soil fungi. Major topics are the mycorrhizal cellular functions using stable isotope tracers and nanoscale map SIMS and the decline mechanisms of the white root rot fungal pathogen associated with changes of soil microbial communities by hot water treatment.

keywords:symbioses, soil-borne plant disease, orchid mycorrhiza, arbuscular mycorrhiza, soil microbial community, ultrastructure, secondary ion mass spectrometry

  1. Allocation of Carbon from an Arbuscular Mycorrhizal Fungus, Gigaspora margarita, to Its Gram-Negative and Positive Endobacteria Revealed by High-Resolution Secondary Ion Mass Spectrometry. Microorganisms (2021)
  2. From imaging to functional traits in interactions between roots and microbes. In: Methods in Rhizosphere Biology Research. Springer (2019)
  3. Uptake and intraradical immobilization of cadmium by arbuscular mycorrhizal fungi as revealed by stable isotope tracer and synchrotron radiation µX-ray fluorescence analysis. Microbes Environ (2018)
佐藤 明子 教授 / SATOH Akiko Professor


Organelles maintain their shapes and functions as the equilibrium of membrane flow into and out of them. We are trying to identify the dynamics of Golgi apparatus, and understand its function on the biogenesis of the secretory and membrane proteins.

keywords:Golgi stacks, cisternae, Trans Golgi Network (TGN)

  1. Rab6 is required for multiple apical transport pathways but not for basolateral transport pathway in Drosophila photoreceptors/PLOS Genetics/2016
  2. Recycling endosomes are attached to trans-side of Golgi units both in Drosophila and mammalian cells/J. Cell Sci./2020
  3. Sec71 separates Golgi stacks in Drosophila S2 cells/J. Cell Sci./2020
竹田 一彦 教授 / TAKEDA Kazuhiko Professor

環境中の微量物質活性酸素マイクロプラスチックなどの分析方法の確立とそれらの地球環境に対する影響評価。 主に分析化学的プローチによる手法開発と、海洋や河川、大気などのフィールド調査の融合による研究。

I am a professional environmental scientist applying analytical chemistry in the aquatic environments and atmosphere. The current works are focused on photochemistry and their dynamics of 1) microplastics, 2) iodine, 3) reactive oxygen species, and 4) pollutants in environments. We are approaching these themes with laboratory work and fieldwork.

keywords:analytical Chemistry, environmental chemistry, microplastics, iodine, reactive oxygen species

  1. Migration of terephthalate from scraps of poly(ethylene terephthalate)(PET) in water and artificial seawater. Sci Total Environ 838: Article 156053 (2022)
  2. Factors controlling the degradation of hydrogen peroxide in river water, and the role of riverbed sand. Sci Total Environ 716: Article 136971 (2020)
  3. The iodide and iodate distribution in the Seto Inland Sea, Japan. Aquat Geochem 23: 315-330 (2017)
中坪 孝之 教授 / NAKATSUBO Takayuki Professor

河川流域北極ツンドラ硫気荒原などをフィールドに、生態系における個々の生物の役割を明らかにすることによって、 生態系の構造と機能の理解、環境変動が生態系に与える影響の予測を目指しています。

My research fields are ecosystem ecology and plant ecology. Recent research subject of my laboratory is the impact of alien species on the structure and function of ecosystems. In addition, I have been working on the impact of climate change on the Arctic terrestrial ecosystem for more than 20 years.

keywords:alien species, arctic, climate change, ecosystem ecology, plant ecology

  1. Effects of climate warming on the production of the pioneer moss Racomitrium japonicum: seasonal and year-to-year variations/J. Plant Res./2021
  2. Annual respiration of Japanese mud snail Batillaria attramentaria in an intertidal flat: its impact on ecosystem carbon flows/Landsc. Ecol. Eng./2019
  3. Distribution and stress tolerance of Fimbristylis dichotoma subsp. podocarpa(Cyperaceae)growing in highly acidic solfatara fields/Ecol. Res./2018
山田 俊弘 教授 / YAMADA Toshihiro Professor

主に、インドネシアマレーシアミャンマーなどの熱帯林で研究をしています。熱帯林は生物多様性が高いことで知ら れています。私は、どの程度生物多様性が高いのか?、や、なぜ生物多様性が高いのか?について調べています。また、熱帯域は生物多様性の喪失が大きいことも知られています。生物多様性を保全する方策に関する研究も行っています。

I mainly study the tropical forests in Indonesia, Malaysia, Myanmar and so on. Tropical forests are known for their mega-biodiversities. At the same time, they are known for a large loss of biodiversity. I am conducting research on measures to conserve tropical biodiversity.

keywords:biodiversity, conservation biology, tropical rain forests

  1. The Forest Observation System, building a global reference dataset for remote sensing of forest biomass. Scientific data 6 (2019)
  2. TRY plant trait database – enhanced coverage and open access. Global Change Biology (2020)
  3. Dynamics of Tree Species Diversity in Unlogged and Selectively Logged Malaysian Forests. Scientific Reports 8:1024 (2018)


和崎 淳 教授 / WASAKI Jun Professor


Main research topic is plant nutrition (especially phosphorus) and the dynamics in the rhizosphere. Strategies of P mobilization by plants are actively investigated, such as cluster root formation, root exudates, and plant-microbial interactions. We are also trying to apply the strategy on improvement of P use efficiency.

keywords:rhizosphere, phosphorus, root exudates, cluster roots

  1. AtALMT3 is involved in malate efflux induced by phosphorus deficiency in Arabidopsis thaliana root hairs. Plant Cell Physiol. 60: 107-115 (2019)
  2. P and N deficiency change the relative abundance and function of rhizosphere microorganisms during cluster root development of white lupin (Lupinus albus L.). Soil Sci. Plant Nutr. 64: 686-696. (2018)
  3. Formation of dauciform roots by Japanese native Cyperaceae and their contribution to phosphorus dynamics in soils. Plant Soil, 461:107- 118 (2021).
ヴィレヌーヴ 真澄美 教授 / VILLENEUVE Masumi Professor


My research area is colloid and interface science. From materials to biomembranes, what we call soft matter is the subject of my research. Currently, I study the thermodynamics and dynamics of self-assembled monolayers at interfaces and the swelling mechanism of gluten-free, additive-free rice bread.

keywords:colloid, interface, thermodynamics, rheology, surfactants, lipids, starch

  1. Roles of a-methyl trans-cyclopropane groups in behavior of mixed mycolic acid monolayers/BBA-Biomembrane 1861: 441 (2019)
  2. Uptake of iron (III)-ethylenediamine-N,N,N',N'-tetraacetic acid complex by phosphatidylcholine lipid film. Part II. Effect of film curvature/ Chem. Phys. Lipids 210: 14 (2018)
  3. Development of gluten-free rice bread: Pickering stabilization as a possible batter-swelling mechanism/LWt-Food Sci. Tech. 79: 632 (2017)
岩本 洋子 准教授 / IWAMOTO Yoko Associate Professor


We are working on atmospheric aerosols. Aerosol particles can act as nuclei of cloud droplets, or can be a source of nutrients for plants on the sea/land surface. To understand the effects of aerosols on the global climate and biogeochemical cycles, we conduct atmospheric observations in various environments.

keywords:aerosol, climate, cloud, biogeochemical cycles

  1. Contribution of oceanic aerosol particles to cloud condensation nuclei, Earozoru Kenkyu, 35(3), 192-198, 2020
  2. Simultaneous measurement of CCN activity and chemical composition of fine-mode aerosols at Noto Peninsula, Japan, in autumn 2012/ Aerosol Air Qual. Res./2016
  3. Spatial variation of biogenic and crustal elements in suspended particulate matter from surface waters of the North Pacific and its marginal seas/Progr. Oceanogr./2014
小林 勇喜 准教授 / KOBAYASHI Yuuki Associate Professor


Although G protein-coupled receptors (GPCRs) play important roles as receptors that mediate various life phenomena, a detailed understanding of their functions is limited. My main recent research topic is the analysis of GPCRs localized in primary cilia. We are aiming for a breakthrough in the field of neuroscience.

keywords:GPCR, primary cilia, endocrinology, neuroscience

  1. Properties of primary cilia in melanin-concentrating hormone receptor 1-bearing hippocampal neurons in vivo and in vitro. Neurochem Int 142 : 104902. (2021)
  2. New perspectives on GPCRs: GPCR heterodimer formation (melanocortin receptor) and GPCR on primary cilia (melanin concentrating hormone receptor). Gen Comp Endocrinol 293 : 114474. (2020)
  3. Characterization of functional primary cilia in human induced pluripotent stem cell-derived neurons. Neurochem Res 44 : 1736–1744. (2019)
土谷 彰男 准教授 / TSUCHIYA Akio Associate Professor


Land use changes and heat balance components. Sap flow of capoeira and evapotranspiration over a pasture. Irradiance under a primary forest and an agricultural forest. Historical changes in Amazonian environments and the roles of Large-scale Biosphere-Atmosphere Experiments in Amazonia (LBA).

keywords:Amazon, Amazonia, environment, ambiente


  1. Differences in irradiance characteristics between Syzygium malaccense and Magnifera indica caused by their tree forms. Eco-habitat 27 (1): 65-74. (2021)
  2. Changes in CO2 concentration within shallow soils originating from solar radiation and rainwater in Central Amazonia. Jpn. J. Biometeor. 53-2: 93-93 (2016)
  3. Short-term responses of tree growth rings in natural gaps for forest management. In: F.M.B. Romero, R.B. Castro & J.C.R. Tello (eds), Estudos dendrológicos e ecológicos na Amazônia: oportunidades e experiências, 66-86. INPA, Manaus, Brazil. (2022)
中林 雅 准教授 / NAKABAYASHI Miyabi Associate Professor


We study the ecology and behavior of animals, mainly mammals, through field work. We also focus on plant-animal interactions such as seed dispersal and pollination.

keywords:mammal, ecology, behavior, field work

  1. Temporal activity patterns suggesting niche partitioning of sympatric carnivores in Borneo, Malaysia. Sci Rep 11: 19819 (2021)
  2. Limited directed seed dispersal in the canopy as one of the determinants of the low hemi-epiphytic figs’ recruitments in Bornean rainforests. PLOS ONE: pone.0217590 (2019)
  3. Horizontal habitat preference of three sympatric Paradoxurinae civet species in a small area in Sabah, Malaysian Borneo. Eur J Wildl Res 63: 2 (2017)
根平 達夫 准教授 / NEHIRA Tatsuo Associate Professor


Life science is explored by organic chemistry, specifically, organic synthesis and organic structure analysis. Synthesis of useful probes, chirality analysis by circular dichroism, and structure elucidation of natural products are conducted.

keywords:organic synthesis, structural organic chemistry, natural product chemistry, circular dichroism

  1. Development of a Universal Ellipsoidal Mirror Device for Fluorescence Detected Circular Dichroism (FDCD) – Elimination of Polarization Artifacts, Appl Spectr 59: 121-125 (2005)
  2. A sensitive method based on fluorescence-detected circular dichroism for protein local structure analysis, Anal Biochem 430: 179-184 (2012)
  3. Natural Dolapyrrolidone: Isolation and Absolute Stereochemistry of a Substructure of Bioactive Peptides, Chirality 32: 1152-1159 (2020)
彦坂 暁 准教授 / HIKOSAKA Akira Associate Professor


We are studying the early evolution of animals, the evolution of ontogeny, and the evolution of endosymbiosis with microalgae using an acoel flatworm, Praesagittifera naikaiensis, living in the Seto Inland Sea.

keywords:Acoela, evolution, endosymbiosis, Seto Inland Sea, Praesagittifera naikaiensis

  1. Geographical Distribution and Genetic Diversity of Praesagittifera naikaiensis(Acoelomorpha) in the Seto Inland Sea, Japan. Zool Sci 37:314–9. (2020)
  2. Multiple massive domestication and recent amplification of Kolobok superfamily transposons in the clawed frog Xenopus. Zoological Lett 4:17. (2018)
  3. Genome evolution in the allotetraploid frog Xenopus laevis. Nature 538:336–343. (2016)
渡邊 千穂 准教授 / WATANABE Chiho Associate Professor

物質的な側面から生命や疾病を読み解くことを目指し、生体膜を模倣したリポソームや高分子液滴(エマルション)などのin vitro細胞モデル(人工細胞)を用いたプロジェクトに取り組んでいます。

I work on projects using in vitro cell models (artificial cells) such as polymer solutions, polymer droplets (emulsions), and liposomes (lipid membranes). My aim is to understand “life” from materials and explore connections between them. I am currently interested in neurodegenerative disease and lipid roles in liquid-liquid phase separation.

keywords:lipid membrane, artificial cell, polymer solutions, liposomes, emulsions

  1. Membrane Surface Modulates Slow Diffusion in Small Crowded Droplets /Langmuir/2021
  2. Quantitative Analysis of Membrane Surface and Small Confinement Effects on Molecular Diffusion/J. Phys. Chem. B/2020
  3. On the possible structural role of single chain sphingolipids Sphingosine and Sphingosine 1-phosphate in the amyloid-β peptide interactions with membranes. Consequences for Alzheimer’s disease development/Colloids Surf. A/2016
戸田 求 講師 / TODA Motomu Associate Professor or Lecturer

主要研究課題:森林生態系を対象としたエネルギー・炭素循環 研究手法:野外観測、数値モデルシミュレーション、デジタル画像解析など 近年の研究課題:(a)気候変動に関連する自然撹乱からの生態系応答(b)老齢林の高い炭素吸 収量を生み出すメカニズム解明 (c)デジタル画像処理を駆使した森林生態系の機能・構造評価

My research interests are biosphere-atmosphere interaction, carbon and water cycle in terrestrial ecosystems, digital visualisation of canopy structure, near-surface remote sensing operations and process-based ecosystem modeling.

keywords:terrestrial carbon cycle, macro- and micro-climates; atmosphere–forest dynamics modeling, climate change

  1. A Bayesian framework to evaluate parameter and predictive inference of a simple soil respiration model in a temperate forest in western Japan. Ecological Modelling(2020)
  2. Estimation of plant area index and phenological transition dates from digital repeat photography and radiometric approaches in a hardwood forest in the Northeastern United States. Agricultural and Forest Meteorology(2017)
  3. Single level turbulence measurements to determine roughness parameters of complex terrain. Journal of Geophysical ResearchAtmosphere)(2003)
勝山 千恵 助教 / KATSUYAMA Chie Assistant Professor


My research themes are element cycles and dynamics caused by soil microorganisms. I am trying to elucidate the interactions between soil microorganisms, such as a mycorrhizal fungus, endobacteria, a fungal pathogen, and soil bacteria and fungi around fungal hyphae (hyphosphere), by using stable isotope tracers and microbial ecological methods.

keywords:soil microorganisms, white root rot fungal pathogen, mycorrhiza, endobacteria, hyphosphere, element cycle, stable isotope tracer, gas chromatography/mass spectrometry (GC/MS), microbial ecology

  1. Overview of recent researches on nitrifying microorganisms in soil. Soil Sci Plant Nutr 67: 619-632. (2021)
  2. Occurrence and potential activity of denitrifiers and methanogens in groundwater at 140 m depth in Pliocene diatomaceous mudstone of northern Japan. FEMS Microbiol Ecol 86: 532-543. (2013)
  3. Allocation of carbon from an arbuscular mycorrhizal fungus, Gigaspora margarita, to its gram-negative and positive endobacteria revealed by high-resolution secondary ion mass spectrometry. Microorganisms 9: 2597. (2021)
中川 直樹 助教 / NAKAGAWA Naoki Assistant Professor


Using mutants with altered plant mitochondrial function and plant growth regulators, we aim to clarify the relationships between mitochondria and various traits that have been overlooked.

keywords:plant hormone

  1. The putative peptide gene FEP1 regulates iron deficiency response in Arabidopsis. Plant Cell Physiol. 59: 1739-52 (2018)
  2. Sugar treatment inhibits IAA‐induced expression of endo‐1,3:1,4‐β‐glucanase EI transcripts in barley coleoptile segments Physiol. Planta. 139: 413-420 (2010)
  3. A mutation in At-nMat1a, which encodes a nuclear gene having high similarity to group II intron maturase, causes impaired splicing of mitochondrial NAD4 transcript and altered carbon metabolism in Arabidopsis thaliana. Plant Cell Physiol. 47: 772 - 83 (2006)
平野 哲男 助教 / HIRANO Tetsuo Assistant Professor


I have discovered that CCDC26-RNA, one of the enigmatic "non-coding RNAs", is involved in the oncogenic transformation of myeloid leukemia cells. Interestingly, I have recently found that this molecule is also involved in developmental stage-specific gene regulation of erythroid cells.

keywords:tumorigenesis, double minute chromosomes, gene amplification, leukemia, mt DNA, HL-60

  1. Long noncoding RNA CCDC26 as a modulator of transcriptional switching between fetal and embryonic globins./BBA- MCR/2021 
  2. Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression./Mol.Cancer/2015 
  3. Genes encoded within 8q24 on the amplicon of a large extrachromosomal element are selectively repressed during the terminal differentiation of HL-60 cells./Mutat.Res./2008
成松 勇樹 特任助教 / NARIMATSU Yuki Assistant Professor (Special Appointment)


We are interested in the mechanisms through which neuropeptides and neurons existing within the brain govern an animal's feeding behavior and fat accumulation. We aim to contribute to resolving issues related to obesity and metabolic diseases in the future.

keywords:neuroendocrinology, energy metabolism, obesity, metabolic diseases

  1. Hypothalamic Overexpression of Neurosecretory Protein GL Leads to Obesity in Male C57BL/6J Mice.Neuroendocrinology 112:606–620 (2022)
  2. Neurosecretory Protein GL Accelerates Liver Steatosis in Mice Fed Medium-Fat/Medium-Fructose Diet. Int J Mol Sci 23:2071 (2022)
  3. Subcutaneous infusion of neurosecretory protein GL promotes fat accumulation in mice. 7:e07502 (2021)