Aquatic Pathology


The Laboratory of Aquatic Pathology studies infectious diseases of cultured and wild fin fish and shellfish, particularly those caused by viruses and bacteria, in order to reveal infection mechanisms and develop effective control measures of the diseases.

1)Studies on fish-virus interactions using model fish(Okinaka, Y.)


Fish and shellfish diseases, Fish pathogens, Fish defenses, Disease control



Betanodavirus in a nerve cell of fish

Betanodavirus in a nerve cell of fish

Edwardsiella ictaluri-specific bacteriophage

Edwardsiella ictaluri-specific bacteriophage

Recent Publications

Adachi, K., Sumiyoshi, K., Ariyasu, R., Yamashita, K., Zenke, K., and Okinaka, Y. (2010) Susceptibilities of medaka (Oryzias latipes) cell lines to a betanodavirus. Virol. J. 7:150.

Hata N., Okinaka, Y., Iwamoto, T., Kawato, Y., Mori, K., and Nakai, T. (2010) Identification of RNA regions that determine temperature sensitivity in betanodaviruses. Arch. Virol. 155:1597–1606.

Ito, Y., Okinaka, Y., Mori, K., Sugaya, T., Nishioka, T., Oka, M., and Nakai, T. (2008) The variable region of RNA2 is sufficient to determine host specificity in betanodaviruses. Dis. Aquat. Org. 79:199–205.

Furusawa, R., Okinaka, Y., and Nakai, T. (2006) Betanodavirus infection in the freshwater model fish medaka (Oryzias latipes). J. Gen. Virol. 87:2333–2339.