Food Microbiology and Hygiene


The laboratory of Food Microbiology and Hygiene conducts basic and applied research projects on food-borne or waterborne pathogens that cause infectious diseases or food poisoning impacting on human health and food safety using food hygienic, microbiological and genetic approaches.

1) Ecology of foodborne bacterial pathogens in environments; microbial control using hurdle technology in foods; antibacterial activity of plant-extracts and its use in food preservation (Nakano, H.)

2) Pathogenicity, antimicrobial resistance and retron reverse transcriptases in foodborne pathogens; detection and disinfection of norovirus (Shimamoto, T.)

3) Molecular microbiology of foodborne pathogens researching signal transduction systems for their growth and pathogenicity; screening, functional and structural analyses, and application of specific antimicrobial agents such as endolysins (Narita, H.)


Food-borne pathogens, Microbial control, Reverse transcriptase,Antimicrobial resistance, Endolysin, Norovirus

DNA analysis of Salmonella isolated from the natural environment

DNA analysis of Salmonella isolated from the natural environment

Induction of mutations in Escherichia coli by reverse transcriptase

Induction of mutations in Escherichia coli by reverse transcriptase

Specific cell lysis of Clostridium perfringens by endolysin

Recent Publications

Cui,H., Gabriel,A., Nakano,H., (2011) Heat-sensitizing effects of plant extracts on Clostridium spp. spores. Food Control 22: 99-104.

Gabriel, A., Nakano,H., (2011) Effects of culture conditions on the subsequent heat inactivation of E. coli O157:H7 in apple juice. Food Control 22: 456-1460.

Cui, H., Gabriel, A., Nakano, H., (2010) Antimicrobial efficacies of plant extracts and sodium nitrite against Clostridium botulinum. Food Control 21: 1030-1036.

Gabriel.A., Nakano,H., (2010) Influences of simultaneous physicochemical stress exposures on injury and subsequent responses of E.coli O157:H7 to resuscitative and inactivate challenges. Int.J.FoodMicrobiol. 139: 182-192.

Elnahriry, S. S., Khalifa, H. O., Soliman, A. M., Ahmed, A. M., Hussein, A. H., Shimamoto, T., Shimamoto, T. (2016) Emergence of plasmid-mediated colistin resistance gene, mcr-1, in a clinical Escherichia coli isolate from Egypt. Antimicrob. Agents Chemother. 60: 3249-3250.

Ahmed, A. M., Shimamoto, T. (2015) Molecular analysis of multidrug resistance in Shiga toxin-producing Escherichia coli O157:H7 isolated from meat and dairy products. Int. J. Food Microbiol. 193: 68-73.

Kamimoto, M., Nakai, Y., Tsuji, T., Shimamoto, T., Shimamoto, T. (2014) Antiviral effects of persimmon extract on human norovirus and its surrogate, bacteriophage MS2. J. Food Sci. 79: M941-M946.

Shimamoto, T., Ahmed, A. M., Shimamoto, T. (2013) A novel retron of Vibrio parahaemolyticus is closely related to retron-Vc95 of Vibrio cholerae. J. Microbiol. 51: 323-328.

Tamai, E., Yoshida, H., Sekiya, H., Nariya, H., Miyata, S., Okabe, A., Kuwahara, T., Maki, J., Kamitori, S. (2014) X-ray Structure of a Novel Endolysin Encoded by Episomal Phage phiSM101 of Clostridium perfringens. Mol. Microbiol. 92: 326-337.

Yamaguchi, Y., Nariya, H., Park, J. H., Inouye, M. (2012) Inhibition of specific gene expressions by protein-mediated mRNA interference. Nat. Commun. 3: 607

Nariya, H., Miyata, S., Kuwahara, T., Okabe, A. (2011) Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens. Appl. Environ. Microbiol. 77: 8439-8441.

Nariya, H., Miyata, S., Tamai, E., Sekiya, H., Maki, J., Okabe, A. (2011) Identification and characterization of a putative endolysin encoded by episomal phage phiSM101 of Clostridium perfringens. Appl. Microbiol. Biotechnol. 90: 1973-1979.


Professor     Nakano, H.
Professor     Shimamoto, T.
Associate Professor     Nariya, H.

>> Go to the Laboratory's Home page