• homeHome
  • 研究
  • [Research] A Simpler Way to Choose the Sex of Offspring by Separating X and Y Sperm

[Research] A Simpler Way to Choose the Sex of Offspring by Separating X and Y Sperm

Differential gene activity by the two sex chromosomes allows X-bearing sperm to be slowed down

sperm

Both X sperm and Y sperm swim to oocyte for fertilization. The probability to bind and penetrate to oocyte is same; however, under the specific condition, the ration of X sperm and Y sperm to reach to oocyte is changed. Credit: Gerd Altmann from Pixabay

A simple, reversible chemical treatment can segregate X-bearing sperm from Y-bearing sperm, allowing dramatic alteration of the normal 50/50 male/female offspring ratio, according to a new study by Masayuki Shimada and colleagues at Hiroshima University, published on August 13 in the open-access journal PLOS Biology. The study was performed in mice, but the technique is likely to be widely applicable to other mammals as well.

READ FULL STORY HERE

Full bibliographic information

Journal: PLOS Biology
Title: Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm
Authors: Takashi Umehara, Natsumi Tsujita, Masayuki Shimada
https://doi.org/10.1371/journal.pbio.3000398

[Media Contact]
Professor Masayuki Shimada
Graduate School of Integrated Sciences for Life, Hiroshima University

E-mail: mashimad*hiroshima-u.ac.jp (Please replace * with @)


up